
Sep 17, 2026
Prelude Wins FDA Clearance to Move Breast Cancer Drug to Trial
Prelude Therapeutics Inc. has received FDA clearance to initiate a Phase 1 trial for PRT13722, an experimental KAT6A-targeting breast cancer drug. The trial will investigate the drug as a monotherapy and in combination with other treatments for advanced or metastatic hormone receptor-positive, HER2-negative breast cancer. Prelude's approach focuses on selectively degrading KAT6A to improve efficacy and safety compared to dual KAT6A/B inhibitors.
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