AnaptysBio Inc (ANAB)
Insider transactions
A complete record of Form 4 filings tracking every share acquisition and disposal by executives, directors, and senior officers. Filterable by date range and transaction type, the table exposes the direct market actions of those with the deepest knowledge of a company's operations — providing a factual, data-driven signal of internal conviction that complements traditional fundamental and technical analysis.
Transaction date | Executive | Executive Title | Security Type | Acquisition / Disposal | Shares | Share price |
|---|---|---|---|---|---|---|
| Oct 1, 2026 | RENTON, HOLLINGS | Director | Common Stock | Disposal | 5,000 | $49.87 |
| Oct 1, 2026 | RENTON, HOLLINGS | Director | Common Stock | Acquisition | 5,000 | $0 |
| Sep 15, 2026 | ORWIN, JOHN A | Director | Common Stock | Acquisition | 1,300 | $0 |
| Sep 15, 2026 | ORWIN, JOHN A | Director | Restricted Stock Unit | Disposal | 1,300 | $0 |
| Sep 15, 2026 | ORWIN, JOHN A | Director | Restricted Stock Unit | Acquisition | 1,300 | $0 |
| Jun 15, 2026 | ORWIN, JOHN A | Director | Restricted Stock Unit | Disposal | 6,030 | $0 |
| Jun 15, 2026 | RENTON, HOLLINGS | Director | Common Stock | Acquisition | 6,030 | $0 |
| Jun 15, 2026 | ORWIN, JOHN A | Director | Common Stock | Acquisition | 6,030 | $0 |
| Jun 15, 2026 | SCHMID, JOHN P. | Director | Common Stock | Acquisition | 6,030 | $0 |
| Jun 15, 2026 | RENTON, HOLLINGS | Director | Restricted Stock Unit | Disposal | 6,030 | $0 |
| Jun 15, 2026 | SCHMID, JOHN P. | Director | Restricted Stock Unit | Disposal | 6,030 | $0 |
| Jun 15, 2026 | ORWIN, JOHN A | Director | Restricted Stock Unit | Acquisition | 6,030 | $0 |
| Jun 15, 2026 | RENTON, HOLLINGS | Director | Restricted Stock Unit | Acquisition | 6,030 | $0 |
| Jun 15, 2026 | SCHMID, JOHN P. | Director | Restricted Stock Unit | Acquisition | 6,030 | $0 |
| May 11, 2026 | MURPHY, CHRISTOPHER M. | Chief Financial Officer | Restricted Stock Units | Acquisition | 25,765 | $0 |
| May 11, 2026 | HUGHES, OWEN | Director | Restricted Stock Units | Acquisition | 11,250 | $0 |
| Apr 27, 2026 | GRAY, SUSANNAH | Director | Restricted Stock Unit | Acquisition | 11,250 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Disposal | 3,311 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Acquisition | 194,900 | $0 |
| Apr 20, 2026 | ANAPTYSBIO,, INC | 10% Owner | Common Stock, par value $0.001 per share | Disposal | 100 | n/a |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 16,510 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Disposal | 194,900 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Acquisition | 10,600 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Disposal | 16,510 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Disposal | 11,000 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Disposal | 9,200 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Acquisition | 16,510 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Acquisition | 379,620 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Acquisition | 9,200 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Acquisition | 11,000 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Acquisition | 8,250 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Disposal | 11,000 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Disposal | 10,600 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Disposal | 9,200 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Disposal | 6,000 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Disposal | 5,500 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Disposal | 10,600 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 6,000 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 16,510 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 10,600 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 9,200 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 11,000 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Disposal | 379,620 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Acquisition | 133,400 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Disposal | 16,510 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Disposal | 133,400 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 9,200 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 6,000 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 15,000 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 11,000 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 10,600 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Disposal | 16,510 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Acquisition | 305,500 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 15,000 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Disposal | 9,200 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Disposal | 5,500 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Disposal | 6,000 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Disposal | 15,000 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Disposal | 10,600 | $0 |
| Apr 20, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Disposal | 11,000 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Disposal | 8,250 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Disposal | 2,321 | $0 |
| Apr 20, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Disposal | 15,000 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Acquisition | 2,321 | $0 |
| Apr 20, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Acquisition | 3,311 | $0 |
| Apr 20, 2026 | FAGA, DANIEL | Director, President, CEO | Employee Stock Option (right to buy) | Disposal | 305,500 | $0 |
| Mar 30, 2026 | SCHMID, JOHN P. | Director | Common Stock | Disposal | 7,527 | $56.70 |
| Mar 30, 2026 | SCHMID, JOHN P. | Director | Common Stock | Disposal | 12,596 | $55.71 |
| Mar 30, 2026 | SCHMID, JOHN P. | Director | Common Stock | Disposal | 522 | $57.40 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 3,155 | $64.19 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 490 | $59.62 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 510 | $56.61 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 550 | $60.63 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 1,012 | $62.15 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 100 | $65.99 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 3,038 | $65.20 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 2,570 | $57.91 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 2,592 | $63.35 |
| Mar 27, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 3,662 | $58.62 |
| Mar 25, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Acquisition | 34,300 | n/a |
| Mar 12, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Performance Stock Units | Acquisition | 16,667 | $0 |
| Mar 12, 2026 | FAGA, DANIEL | Director, President, CEO | Performance Stock Units | Acquisition | 53,334 | $0 |
| Feb 11, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 10,000 | $54 |
| Feb 11, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Disposal | 10,000 | $0 |
| Feb 11, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 10,000 | $29.70 |
| Feb 11, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Acquisition | 10,000 | $0 |
| Jan 15, 2026 | MARQUET, MAGDA | Director | Common Stock | Acquisition | 11,000 | $26.11 |
| Jan 15, 2026 | MARQUET, MAGDA | Director | Common Stock | Disposal | 1,710 | $48.85 |
| Jan 15, 2026 | MARQUET, MAGDA | Director | Stock Option (right to buy) | Disposal | 11,000 | $0 |
| Jan 15, 2026 | MARQUET, MAGDA | Director | Common Stock | Disposal | 9,290 | $48.12 |
| Jan 15, 2026 | MARQUET, MAGDA | Director | Stock Option (right to buy) | Acquisition | 11,000 | $0 |
| Jan 8, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 14,281 | $44.71 |
| Jan 8, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Disposal | 2,515 | $44.71 |
| Jan 8, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 2,210 | $44.71 |
| Jan 8, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Disposal | 3,650 | $44.71 |
| Jan 7, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Acquisition | 8,525 | n/a |
| Jan 7, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 5,281 | $45.38 |
| Jan 7, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Disposal | 2,235 | $45.11 |
| Jan 7, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Restricted Stock Unit | Disposal | 5,888 | $0 |
| Jan 7, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 5,888 | n/a |
| Jan 7, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Acquisition | 26,838 | n/a |
| Jan 7, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 9,202 | $45.11 |
| Jan 7, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 2,017 | $45.11 |
| Jan 7, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 1,841 | $46.13 |
| Jan 7, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Restricted Stock Unit | Disposal | 8,525 | $0 |
| Jan 7, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 500 | $47.23 |
| Jan 7, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Restricted Stock Unit | Disposal | 6,700 | $0 |
| Jan 7, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Acquisition | 6,700 | n/a |
| Jan 7, 2026 | FAGA, DANIEL | Director, President, CEO | Restricted Stock Unit | Disposal | 26,838 | $0 |
| Jan 7, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Disposal | 1,908 | $45.11 |
| Jan 7, 2026 | FAGA, DANIEL | Director, President, CEO | Restricted Stock Unit | Acquisition | 26,838 | $0 |
| Jan 7, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Restricted Stock Unit | Acquisition | 5,888 | $0 |
| Jan 7, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Restricted Stock Unit | Acquisition | 8,525 | $0 |
| Jan 7, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Restricted Stock Unit | Acquisition | 6,700 | $0 |
| Jan 6, 2026 | JAIN, RITA | Director | Restricted Stock Unit | Acquisition | 4,000 | $0 |
| Jan 6, 2026 | ORWIN, JOHN A | Director | Restricted Stock Unit | Acquisition | 6,000 | $0 |
| Jan 6, 2026 | SCHMID, JOHN P. | Director | Restricted Stock Unit | Acquisition | 4,000 | $0 |
| Jan 6, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Restricted Stock Unit | Disposal | 6,145 | $0 |
| Jan 6, 2026 | MARQUET, MAGDA | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Jan 6, 2026 | SCHMID, JOHN P. | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Jan 6, 2026 | FAGA, DANIEL | Director, President, CEO | Stock Option (right to buy) | Acquisition | 133,400 | $0 |
| Jan 6, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Restricted Stock Unit | Acquisition | 21,400 | $0 |
| Jan 6, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Stock Option (right to buy) | Acquisition | 29,000 | $0 |
| Jan 6, 2026 | RENTON, HOLLINGS | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Jan 6, 2026 | WARE, J. ANTHONY | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Jan 6, 2026 | ORWIN, JOHN A | Director | Stock Option (right to buy) | Acquisition | 8,250 | $0 |
| Jan 6, 2026 | WARE, J. ANTHONY | Director | Restricted Stock Unit | Acquisition | 4,000 | $0 |
| Jan 6, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Restricted Stock Unit | Acquisition | 21,400 | $0 |
| Jan 6, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Restricted Stock Unit | Disposal | 5,245 | $0 |
| Jan 6, 2026 | FENTON, DENNIS M | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Jan 6, 2026 | FAGA, DANIEL | Director, President, CEO | Restricted Stock Unit | Acquisition | 98,600 | $0 |
| Jan 6, 2026 | RENTON, HOLLINGS | Director | Restricted Stock Unit | Acquisition | 4,000 | $0 |
| Jan 6, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Restricted Stock Unit | Acquisition | 17,100 | $0 |
| Jan 6, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Stock Option (right to buy) | Acquisition | 29,000 | $0 |
| Jan 6, 2026 | JAIN, RITA | Director | Stock Option (right to buy) | Acquisition | 5,500 | $0 |
| Jan 6, 2026 | FAGA, DANIEL | Director, President, CEO | Restricted Stock Unit | Disposal | 17,850 | $0 |
| Jan 6, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Acquisition | 5,245 | n/a |
| Jan 6, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Stock Option (right to buy) | Acquisition | 23,200 | $0 |
| Jan 6, 2026 | MARQUET, MAGDA | Director | Restricted Stock Unit | Acquisition | 4,000 | $0 |
| Jan 6, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Restricted Stock Unit | Disposal | 5,545 | $0 |
| Jan 6, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 5,545 | n/a |
| Jan 6, 2026 | FENTON, DENNIS M | Director | Restricted Stock Unit | Acquisition | 4,000 | $0 |
| Jan 6, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Acquisition | 6,145 | n/a |
| Jan 6, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Acquisition | 17,850 | n/a |
| Jan 6, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Restricted Stock Unit | Acquisition | 6,145 | $0 |
| Jan 6, 2026 | FAGA, DANIEL | Director, President, CEO | Restricted Stock Unit | Acquisition | 17,850 | $0 |
| Jan 6, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Restricted Stock Unit | Acquisition | 5,245 | $0 |
| Jan 6, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Restricted Stock Unit | Acquisition | 5,545 | $0 |
| Jan 5, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Disposal | 3,363 | $43.26 |
| Jan 5, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Disposal | 15,309 | $43.26 |
| Jan 5, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 2,983 | $43.26 |
| Jan 5, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Disposal | 4,219 | $43.26 |
| Jan 3, 2026 | FAGA, DANIEL | Director, President, CEO | Restricted Stock Unit | Disposal | 34,677 | $0 |
| Jan 3, 2026 | FAGA, DANIEL | Director, President, CEO | Common Stock | Acquisition | 34,677 | n/a |
| Jan 3, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 7,287 | n/a |
| Jan 3, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Acquisition | 10,555 | n/a |
| Jan 3, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Restricted Stock Unit | Disposal | 10,555 | $0 |
| Jan 3, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Acquisition | 8,292 | n/a |
| Jan 3, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Restricted Stock Unit | Disposal | 8,292 | $0 |
| Jan 3, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Restricted Stock Unit | Disposal | 7,287 | $0 |
| Jan 3, 2026 | FAGA, DANIEL | Director, President, CEO | Restricted Stock Unit | Acquisition | 34,677 | $0 |
| Jan 3, 2026 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Restricted Stock Unit | Acquisition | 7,287 | $0 |
| Jan 3, 2026 | LIZZUL, PAUL F. | Chief Medical Officer | Restricted Stock Unit | Acquisition | 10,555 | $0 |
| Jan 3, 2026 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Restricted Stock Unit | Acquisition | 8,292 | $0 |
| Dec 23, 2025 | WARE, J. ANTHONY | Director | Common Stock | Disposal | 3,900 | $49.58 |
| Dec 23, 2025 | SCHMID, JOHN P. | Director | Common Stock | Disposal | 11,068 | $51 |
| Dec 22, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 10,000 | $51 |
| Dec 22, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Employee Stock Option (right to buy) | Disposal | 10,000 | $0 |
| Dec 22, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Disposal | 10,000 | $50 |
| Dec 22, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Acquisition | 10,000 | $20.16 |
| Dec 22, 2025 | LIZZUL, PAUL F. | Chief Medical Officer | Employee Stock Option (right to buy) | Disposal | 1,500 | $0 |
| Dec 22, 2025 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Acquisition | 1,500 | $18.50 |
| Dec 22, 2025 | LIZZUL, PAUL F. | Chief Medical Officer | Common Stock | Disposal | 1,500 | $50 |
| Dec 22, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 10,000 | $14.02 |
| Dec 22, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Disposal | 10,000 | $0 |
| Dec 22, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Employee Stock Option (right to buy) | Acquisition | 10,000 | $0 |
| Dec 22, 2025 | LIZZUL, PAUL F. | Chief Medical Officer | Employee Stock Option (right to buy) | Acquisition | 1,500 | $0 |
| Dec 22, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Acquisition | 10,000 | $0 |
| Dec 18, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 141 | $46.99 |
| Dec 17, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 10,000 | $14.02 |
| Dec 17, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Disposal | 10,000 | $0 |
| Dec 17, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 10,000 | $46 |
| Dec 17, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Acquisition | 10,000 | $0 |
| Dec 16, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Disposal | 9,365 | $44.62 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Disposal | 7,500 | $0 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Disposal | 5,000 | $0 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 4,195 | $45.24 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 5,000 | $14.02 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Acquisition | 7,500 | $20.16 |
| Dec 16, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Disposal | 6,360 | $45.21 |
| Dec 16, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Common Stock | Acquisition | 10,000 | $20.16 |
| Dec 16, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Employee Stock Option (right to buy) | Disposal | 10,000 | $0 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Common Stock | Disposal | 8,305 | $44.68 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Acquisition | 5,000 | $0 |
| Dec 16, 2025 | LOUMEAU, ERIC J | CHIEF LEGAL OFFICER | Employee Stock Option (right to buy) | Acquisition | 7,500 | $0 |
| Dec 16, 2025 | MULROY, DENNIS | CHIEF FINANCIAL OFFICER | Employee Stock Option (right to buy) | Acquisition | 10,000 | $0 |